Scandinavian Journal of Pain
Volume 1 , Pages S24-S26 , May 2009

Research on genes predisposing for chronic pain: a challenge for pain researchers in Scandinavia

  • Anne-Li Lind

      Affiliations

    • Department of Neuroscience, Genetic Developmental Biology, BMC, Uppsala University, Uppsala, Sweden
    • ,
  • Torsten E. Gordh

      Affiliations

    • Multidisciplinary Pain Centre, Uppsala University Hospital, Uppsala, Sweden
    • Corresponding Author InformationCorresponding author. Torsten E Gordh MD, PhD. Professor, Multidisciplinary Pain Centre, Uppsala University Hospital, S-751 85, Uppsala, Sweden. Tel.: +46 18663000; fax: +46 18503539

References 

  1. Aasvang E , Kehlet H . Chronic postoperative pain: the case of inguinal herniorrhaphy . Br J Anaesth . 2005;95:69–76
  2. Bruce J , Poobalan A , Smith W , Chambers W . Quantitative assessment of chronic postsurgical pain using the McGill Pain Questionnaire . Clin J Pain . 2004;20:70–75
  3. Diatchenko L , Slade G , Nackley A , Bhalang K , Sigurdsson A , Belfer I , et al.   Genetic basis for individual variations in pain perception and the development of a chronic pain condition . Hum Mol Genet . 2005;14:135–143
  4. Foulkes T , Wood J . Pain genes . PLoS Genet . 2008;4:e1000086
  5. Grant A , Scott N , O'Dwyer P . MRC laparoscopic groin hernia trial group. Five-year follow-up of a randomized trial to assess pain and numbness after laparoscopic or open repair of groin hernia . Br J Surg . 2004;91:1570–1574
  6. Javan M , Ahmadiani A , Motamadi F , Kazemi B . Changes in G proteins genes expression in rat lumbar spinal cord support the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia . Neurosci Res . 2005;53:250–256
  7. Kalliomäki M , Sandblom G , Gunnarsson U , Gordh T . Persistent pain after groin hernia surgery: a qualitative analysis of pain and its consequences for quality of life . Acta Anaesthesiol Scand . 2009;53:236–246
  8. Macdonald L , Bruce J , Scott N , Smith W , Chambers W . Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome . Br J Cancer . 2005;92:225–230
  9. Nienhuijs S , Staal E , Strobbe L , Rosman C , Groenewoud H , Bleichrodt R . Chronic pain after mesh repair of inguinal hernia: a systematic review . Am J Surg . 2007;194:394–400
  10. Reynolds KK , Ramey-Hartung B , Jortani SA . The value of CYP2D6 and OPRM1 pharmacogenetic testing for opioid therapy . Clin Lab Med . 2008;28:581–598
  11. Tegeder I, Lötsch J. Current evidence for a modulation of low back pain by human genetic variants. J Cell Mol Med 2009 Feb 17 [Epub ahead of print].
  12. Tegeder I , Costigan M , Griffin RS , Abele A , Belfer I , Schmidt H , et al.   GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence . Nat Med . 2006;12:1269–1277
  13. Yarnitsky D , Crispel Y , Eisenberg E , Granovsky Y , Ben-Nun A , Sprecher E , et al.   Prediction of chronic post-operative pain: pre-operative DNIC testing identifies patients at risk . Pain . 2008;138:22–28

PII: S1877-8860(09)70006-0

doi: 10.1016/S1877-8860(09)70006-0

Scandinavian Journal of Pain
Volume 1 , Pages S24-S26 , May 2009

Article Tools